Spina bifida outcomes from failure of fusion of the neural tube , and is one of the most common malformations of individual structure reviews . The causes of this disorder are varied, including chromosome abnormalities and gene disorders. The cause isn’t known generally. An interview with Dr Matt SilverPregnant women with elevated blood-sugar levels more likely to possess babies with heart defectsResearchers develop accurate method to predict postpartum diabetesLaura Mitchell and co-workers highlight how up to 70 percent of spina bifida cases can be avoided by maternal folic acid supplementation around enough time of conception. The mechanism underlying this protective effect is unknown, state the authors, nonetheless it is likely to consist of genes that regulate folate transport and rate of metabolism.