A restrictive threshold for transfusion may very well be favored because it requires the use of fewer systems of allogeneic reddish cells. However, the results of our secondary analyses create new uncertainty regarding the use of a restrictive threshold for transfusion after cardiac medical procedures. It is complicated to interpret the results of secondary analyses when many statistical tests are performed,37 but the higher rate of recurrence of death in the restrictive-threshold group, which persisted in sensitivity analyses , is a cause for concern. It isn’t clear in what way anemia that was due to the restrictive threshold may possess resulted in an elevated number of deaths.THE CAUSES OF ACNE The increased hormone creation in the puberty stimulates to increased sebum production. The male hormone, testosterone, seem to contribute most. Girls start to create more testosterone in the puberty Also. In other periods Also, altered hormone production may give acne, for example by women in the menopause. Since not absolutely all teens get pimples in any level, the elevated hormone level can’t be the whole reason behind the increased sebum creation.