Despite the fact that the time to AIDS in the group with dual an infection and simultaneous HIV-1 and HIV-2 seroreactivity recorded initial was intermediate , this time did not differ significantly from that in either the group with dual an infection and HIV-2 seroreactivity first or the group with HIV-1 infections only . The hazard ratio for progression to AIDS was 3.12 for HIV-1 illness only as compared with dual illness with HIV-2 seroreactivity initial and was 2.27 for HIV-1 infections only as compared with dual infection with simultaneous HIV-1 and HIV-2 seroreactivity recorded first. The hazard ratio for dual illness with simultaneous HIV-1 and HIV-2 seroreactivity recorded first in comparison with dual illness with HIV-2 seroreactivity first was 1.37 .The researchers found that 56 of the 249 females studied at the University of Chicago Medicine's Cancers Risk Clinic had inherited in least one damaging mutation that increased their risk of breast cancer. Twenty-six of a BRCA1 was had by the individuals mutation. Another 20 patients experienced a BRCA2 mutation. Twelve ladies inherited mutations in additional genes: CHEK2, PALB2, ATM, and PTEN. Two women inherited mutations in two different genes. Patients probably to transport a mutation were those diagnosed with a second primary tumor-a second cancers that developed individually from the initial; 49 % of those females carried an inherited breasts cancer-associated gene mutation.