This pressure exists almost but is particularly intense in China everywhere. It is consequently no real surprise that the many inventive ways to video game the peer-review program to get manuscripts released have come from China. The companies mentioned above that provide fake peer testimonials all come from China and countries in Southeast Asia, & most of the authors involved with these full cases come from the same areas. But it would be a mistake to look at this simply because a Asian or Chinese problem. The nagging problem may be the perverse incentive systems in scientific publishing. Provided that authors are rewarded for publishing many articles and editors are rewarded for publishing them quickly, new means of gaming the original publication models will be invented quicker than new control procedures could be put in place..Burke, B.A., Kashif Jafri, B.A., Benjamin C. French, Ph.D., Julie A. Phillips, Ph.D., Megan L. Mucksavage, M.Sc., Robert L. Wilensky, M.D., Emile R. Mohler, M.D., George H. Rothblat, Ph.D., and Daniel J. Rader, M.D.: Cholesterol Efflux Capability, High-Density Lipoprotein Function, and Atherosclerosis A robust inverse association between the level of high-density lipoprotein cholesterol and the chance of cardiovascular disease has fostered intensive analysis wanting to target HDL fat burning capacity for therapeutic gain.1,2 However, some findings have called into question the hypothesis that pharmacologic boosts in HDL cholesterol levels are necessarily beneficial. Several therapies, including nicotinic acid and fibric acid derivatives, increase HDL cholesterol amounts, but linking these boosts to clinical risk reduction has proved challenging.3,4 Most strikingly, an inhibitor of cholesteryl ester transfer proteins was connected with an increase in the amount of cardiovascular events, despite a 72 percent upsurge in HDL cholesterol amounts.5 Finally, neither rare nor common genetic variants associated with HDL cholesterol levels have been strongly linked to heart disease.6-9 The static measurement of HDL cholesterol levels has inherent limitations as a metric of the functional ramifications of HDL in vivo.